GRB7, GRB10 AND GRB14, ENCODING THE GROWTH FACTOR RECEPTOR-BOUND 7 FAMILY OF SIGNALLING ADAPTOR PROTEINS HAVE OVERLAPPING FUNCTIONS IN THE REGULATION OF FETAL GROWTH AND POST-NATAL GLUCOSE METABOLISM

Grb7, Grb10 and Grb14, encoding the growth factor receptor-bound 7 family of signalling adaptor proteins have overlapping functions in the regulation of fetal growth and post-natal glucose metabolism

Abstract Background The growth factor receptor bound protein underwater treasures sunken medallion 7 (Grb7) family of signalling adaptor proteins comprises Grb7, Grb10 and Grb14.Each can interact with the insulin receptor and other receptor tyrosine kinases, where Grb10 and Grb14 inhibit insulin receptor activity.In cell culture studies they mediat

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Verslaggeving van toegelaten instellingen volkshuisvesting

Dit artikel beschrijft de uitkomsten van het onderzoek naar de wijze waarop woningcorporaties de wijzigingen wella color touch 77 45 in de Woningwet, de daarmee samenhangende regelgeving en RJ 645 hebben verwerkt en toegelicht in de jaarrekening over 2016.Het artikel richt zich op de gevolgen van de verplichte waardering van het vastgoed in exploit

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Reverse extra-anatomic aortic arch debranching procedure allowing thoracic endovascular aortic repair of a chronic ascending aortic aneurysm

A read more 79-year-old woman was admitted with a large chronic dissecting ascending aortic aneurysm starting 5 mm distal to the ostia of the left coronary artery and ending immediately proximal to the innominate artery.A reverse extra-anatomic aortic arch debranching procedure was performed.During the same operative time, through a transapical app

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COPD exacerbations admitted to intensive care unit. Organization, mortality, and noninvasive or invasive mechanical ventilation strategies: are they sufficiently well known?

Antonio M EsquinasIntensive Care Unit, Hospital Morales Meseguer, Murcia, SpainWe read with interest the survival analysis of chronic obstructive pulmonary disease (COPD) patients who are admitted to critical care units with exacerbation, conducted in Saudi Arabia by Alaithan et al.1 This study makes an important contribution on the real practice o

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